CBD
Cannabidiol
C₂₁H₃₀O₂
CBD (cannabidiol) is the second most abundant cannabinoid in cannabis. Unlike THC, it is non-psychoactive and does not produce a "high." CBD has gained widespread attention for its potential therapeutic benefits and is available in many forms including oils, edibles, and topicals.
Effects
Medical Uses
- +FDA-approved for epilepsy (Epidiolex)
- +Anxiety and stress reduction
- +Chronic pain and inflammation
- +Sleep improvement
- +Neurological disorders
- +Skin conditions (topical)
Side Effects
- !Drowsiness
- !Dry mouth
- !Reduced appetite
- !Diarrhea (at high doses)
- !Potential drug interactions
In Detail
CBD interacts with the endocannabinoid system differently than THC. Rather than directly binding to CB1 receptors, it modulates receptor activity and influences other receptor systems including serotonin (5-HT1A) and vanilloid (TRPV1) receptors. This is why CBD can reduce anxiety and inflammation without causing intoxication. CBD may also reduce some negative effects of THC, such as anxiety and paranoia, when the two are consumed together. This interaction is part of what researchers call the "entourage effect." Cannabis strains high in CBD typically have a CBD:THC ratio of 1:1 or higher, with some hemp varieties containing 15-20% CBD and less than 0.3% THC.
Legal Status
Hemp-derived CBD (less than 0.3% THC) is federally legal in the US under the 2018 Farm Bill. FDA-approved as Epidiolex for certain epilepsy conditions. Widely legal internationally, though regulations vary by country.
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Disclaimer: This information is for educational purposes only and should not be considered medical advice. Always consult with a qualified healthcare professional before making decisions about cannabis use.