THC
Tetrahydrocannabinol
C₂₁H₃₀O₂
THC (tetrahydrocannabinol) is the primary psychoactive compound in cannabis. It is responsible for the "high" associated with marijuana use. THC works by binding to cannabinoid receptors (CB1) in the brain and nervous system, affecting mood, perception, and cognition.
Effects
Medical Uses
- +Chronic pain management
- +Nausea and vomiting (chemotherapy)
- +Appetite stimulation (HIV/AIDS, cancer)
- +Muscle spasticity (multiple sclerosis)
- +Insomnia
- +PTSD symptoms
Side Effects
- !Anxiety or paranoia (at high doses)
- !Dry mouth
- !Red eyes
- !Impaired short-term memory
- !Increased heart rate
- !Impaired coordination
In Detail
When people refer to "THC" in cannabis, they almost always mean Delta-9-THC, the most abundant and well-studied psychoactive cannabinoid. THC content in cannabis flower typically ranges from 10% to 30%, with concentrates reaching 60-90%. The compound was first isolated by Dr. Raphael Mechoulam in 1964. THC interacts with the endocannabinoid system, which regulates functions like pain, mood, appetite, and memory. The intensity and character of its effects depend on dosage, strain terpene profile, and individual tolerance.
Legal Status
Legal for medical and/or recreational use in many US states and several countries. Remains federally illegal in the US as a Schedule I substance.
Learn More
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Disclaimer: This information is for educational purposes only and should not be considered medical advice. Always consult with a qualified healthcare professional before making decisions about cannabis use.